International Journal of Antimicrobial Agents
Volume 14, Issue 3 , Pages 231-234 , April 2000

Potentiation of the action of metronidazole on Helicobacter pylori by omeprazole and bismuth subcitrate

  • Leif P Andersen

      Affiliations

    • Department of Clinical Microbiology 7806, National University hospital (Rigshospitalet), Tagensvej 20, DK-2200 Copenhagen, Denmark
    • Corresponding Author InformationCorresponding author. Tel.: +45-35457784; fax +45-35456831
    • ,
  • Hanne Colding

      Affiliations

    • Institute for Medical Microbiology, University of Copenhagen, Copenhagen, Denmark
    • ,
  • Jette E Kristiansen

      Affiliations

    • Department of Clinical Microbiology, Sonderborg Hospital, Sonderborg, Denmark

References 

  1. Megraud F, Brassens-Rabbe MP, Denis F, et al.  Seroepidemiology of Campylobacter pylori infection in various populations. J. Clin. Microbiol. 1989;27:1870–1873
  2. Andersen LP, Rosenstock SJ, Bonnevie O, et al.  Seroprevalence of immunoglobulin G, M, and A antibodies to Helicobacter pylori in an unselected Danish population. Am. J. Epidemiol. 1996;143:1157–1164
  3. Kosunen TU, Hook J, Rautelin HI. Age-dependent increase of Campylobacter pylori antibodies in blood donors. Scand. J. Gastroenterol. 1989;24:110–114
  4. Klein PD, Graham DY, Gaillour A, et al.  Water source as risk factor for Helicobacter pylori infection in Peruvian children. Gastrointestinal Physiology Working Group. Lancet. 1991;337:1503–1506
  5. Kelly SM, Pitcher MC, Farmery SM, et al.  Isolation of Helicobacter pylori from faeces of patients with dyspepsia in the UK. Gastroenterology. 1994;107:1671–1674
  6. Marshall BJ, Warren JR. Unidentified curved bacilli in the stomach of patients with gastritis and peptic ulceration. Lancet. 1984;1:1311–1315
  7. Dunn BE, Cohen H, Blaser MJ. Helicobacter pylori. Clin. Microbiol. Rev. 1997;10:720–741
  8. Andersen LP, Nielsen H. Peptic ulcer: an infectious disease?. Ann. Med. 1993;25:563–568
  9. Lynch DA, Axon AT. Helicobacter pylori, gastric cancer and gastric epithelial kinetics: a review. Eur. J. Gastroenterol. Hepatol. 1995;7:S17–S23
  10. Eidt S, Stolte M. The significance of Helicobacter pylori in relation to gastric cancer and lymphoma. Eur. J. Gastroenterol. Hepatol. 1995;7:318–321
  11. Hopkins RJ, Girardi LS, Tumey EA. Relationship between Helicobacter pylori eradication and reduced duodenal and gastric ulcer recurrence: a review. Gastroenterology. 1996;110:1244–1252
  12. Deltenre M, Jonas C, Otero J, et al.  Strategies for Helicobacter pylori eradication in 1995: a review of international and Belgian experience. J. Physiol. Pharmacol. 1996;47:59–69
  13. Bell GD, Powell KU, Burridge SM, et al.  Reinfection or recrudescence after apparently successful eradication of Helicobacter pylori infection: implications for treatment of patients with duodenal ulcer disease. Q. J. Med. 1993;86:375–382
  14. Kristiansen JE. Antimicrobial activity of non-antibiotics: unusual properties of non-antibiotic drugs create unexpected therapeutic possibilities and lead to new basic insights. Features. ASM News. 1991;57:135–139
  15. Andreasen JJ, Andersen LP. In vitro susceptibility of Campylobacter pylori to cimetidine, sucralfate, bismuth and sixteen antibiotics. Acta Pathol. Microbiol. lmmunol. Scand. Sect. B. 1987;95:147–149
  16. Belli WA, Fryklund J. Partial characterization and effect of omeprazole on ATPase activity in Helicobacter pylori by using permeabilized cells. Antimicrob. Agents Chemother. 1995;39:1717–1720
  17. lwahi T, Hiroshi H, Nakao M, et al.  Lansoprazole, a novel benzimidazole proton pump inhibitor, and its related compounds have selective activity against Helicobacter pylori. Antimicrob. Agents Chemother. 1991;35:490–496
  18. Labenz J, Tillenburg B, Peitz U, et al.  Helicobacter pylori augments the pH-increasing effect of omeprazole in patients with duodenal ulcer. Gastroenterology. 1996;110:725–732
  19. Kristiansen JE. Experiments to illustrate the effect of chlorpromazine on the permeability of the bacterial cell wall. Acta Pathol. Microbiol. Immunol. Scand. Sect. B. 1979;87:317–319
  20. Kristiansen JE. Chlorpromazine: non-antibiotics with antimicrobial activity — new insights in managing resistance?. Curr. Opin. Invest. Drugs. 1993;2:587–591
  21. Kristiansen JE, Amaral L. The potential management of resistant infections with non-antibiotics. J. Antimicrob. Chemother. 1997;40:319–327

PII: S0924-8579(00)00133-3

International Journal of Antimicrobial Agents
Volume 14, Issue 3 , Pages 231-234 , April 2000

Article Tools