International Journal of Antimicrobial Agents
Volume 25, Issue 5 , Pages 409-413, May 2005

Comparative pharmacodynamics of the new fluoroquinolone ABT492 and levofloxacin with Streptococcus pneumoniae in an in vitro dynamic model

  • Alexander A. Firsov

      Affiliations

    • Department of Pharmacokinetics and Pharmacodynamics, Gause Institute of New Antibiotics, Russian Academy of Medical Sciences, 11 Bolshaya Pirogovskaya Street, Moscow 119021, Russia
    • Corresponding Author InformationCorresponding author. Tel.: +7 95 708 3341; fax: +7 95 245 0295.
  • ,
  • Irene V. Alferova

      Affiliations

    • Department of Pharmacokinetics and Pharmacodynamics, Gause Institute of New Antibiotics, Russian Academy of Medical Sciences, 11 Bolshaya Pirogovskaya Street, Moscow 119021, Russia
  • ,
  • Maria V. Smirnova

      Affiliations

    • Department of Pharmacokinetics and Pharmacodynamics, Gause Institute of New Antibiotics, Russian Academy of Medical Sciences, 11 Bolshaya Pirogovskaya Street, Moscow 119021, Russia
  • ,
  • Irene Yu. Lubenko

      Affiliations

    • Department of Pharmacokinetics and Pharmacodynamics, Gause Institute of New Antibiotics, Russian Academy of Medical Sciences, 11 Bolshaya Pirogovskaya Street, Moscow 119021, Russia
    • Institute of Normal Physiology, Russian Academy of Medical Sciences, Moscow, Russia
  • ,
  • Yury A. Portnoy

      Affiliations

    • Department of Pharmacokinetics and Pharmacodynamics, Gause Institute of New Antibiotics, Russian Academy of Medical Sciences, 11 Bolshaya Pirogovskaya Street, Moscow 119021, Russia
  • ,
  • Stephen H. Zinner

      Affiliations

    • Mount Auburn Hospital, Harvard Medical School, Cambridge, MA, USA

Received 8 November 2004; accepted 9 February 2005.

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PII: S0924-8579(05)00048-8

doi:10.1016/j.ijantimicag.2005.02.004

International Journal of Antimicrobial Agents
Volume 25, Issue 5 , Pages 409-413, May 2005