International Journal of Antimicrobial Agents
Volume 34, Issue 3 , Pages 215-219 , September 2009

Anti-inflammatory and antimicrobial effects of garlic and synergistic effect between garlic and ciprofloxacin in a chronic bacterial prostatitis rat model

Received 27 December 2008 ,Accepted 5 February 2009.

References 

  1. Nickel JC, Downey J, Hunter D, Clark J. Prevalence of prostatitis-like symptoms in a population based study using the National Institutes of Health Chronic Prostatitis Symptom Index. J Urol. 2001;165:842–845
  2. Collins MM, Stafford RS, O’Leary MP, Barry MJ. How common is prostatitis? A national survey of physician visits. J Urol. 1998;159:1224–1228
  3. Moon TD, Hagen L, Heisey DM. Urinary symptomatology in younger men. Urology. 1997;50:700–703
  4. Wagenlehner FME, Weidner W, Naber KG. Therapy for prostatitis, with emphasis on bacterial prostatitis. Expert Opin Pharmacother. 2007;8:1–8
  5. Nickel JC. Antibiotics for bacterial prostatitis. J Urol. 2000;163:1407
  6. Shoskes DA, Manickam K. Herbal and complementary medicine in chronic prostatitis. World J Urol. 2003;21:109–113
  7. Lee YS, Han CH, Kang SH, Lee SJ, Kim SW, Shin OR, et al. Synergistic effect between catechin and ciprofloxacin on chronic bacterial prostatitis rat model. Int J Urol. 2005;12:383–389
  8. Choi YS, Cho YH, Han CH. Synergistic effect between ginsenoside or Urovaxom® with ciprofloxacin on chronic bacterial prostatitis rat model. Korean J Urol. 2007;48:849–857
  9. Erdinc D, IIker D. Is garlic a promising food for benign prostatic hyperplasia and prostate cancer?. Mol Nutr Food Res. 2007;51:1319–1323
  10. Ruddock PS, Liao M, Foster BC, Lawson L, Arnason JT, Dillon JA. Garlic natural health products exhibit variable constituent levels and antimicrobial activity against Neisseria gonorrhoeae, Staphylococcus aureus and Enterococcus faecalis. Phytother Res. 2005;19:327–334
  11. Amagase H, Petesch BL, Matsuura H, Kasuga S, Itakura Y. Intake of garlic and its bioactive components. J Nutr. 2001;131(3s):955S–9562S
  12. Key TJ, Silcocks PB, Davey GK, Appleby PN, Bishop DT. A case–control study of diet and prostate cancer. Br J Cancer. 1997;76:678–687
  13. Galeone C, Pelucchi C, Talamini R, Negri E, Dal Maso L, Montella M, et al. Onion and garlic intake and the odds of benign prostatic hyperplasia. Urology. 2007;70:672–676
  14. Naber KG, Sörgel F, Kees F, Jaehde U, Schumacher H. Pharmacokinetics of ciprofloxacin in young (healthy volunteers) and elderly patients, and concentrations in prostatic fluid, seminal fluid, and prostatic adenoma tissue following intravenous administration. Am J Med. 1989;87(5A):57S–59S
  15. Nickel JC, Olson ME, Barabas A, Benediktsson H, Dasgupta MK, Costerton JW. Pathogenesis of chronic bacterial prostatitis in an animal model. Br J Urol. 1990;66:47–54
  16. McGuire EJ, Lytton B. Bacterial prostatitis: treatment with trimethoprim–sulfamethoxazole. Urology. 1976;7:499–500
  17. Izzo AA, Capasso R, Capasso F. Eating garlic and onion: a matter of life or death. Br J Cancer. 2004;91:194
  18. Rahman K. Garlic and aging: new insights into an old remedy. Ageing Res Rev. 2003;2:39–56
  19. Rahman K, Lowe GM. Garlic and cardiovascular disease: a critical review. J Nutr. 2006;136(3 Suppl):736S–740S
  20. Max HP, Edzard E. Clinical effectiveness of garlic (Allium sativum). Mol Nutr Food Res. 2007;51:1382–1385
  21. Roger H, Mino C, Nashia S. Thiolsulfinate allicin from garlic: inspiration for a new antimicrobial agent. Ann N Y Acad Sci. 2005;1056:234–241
  22. Eja ME, Asikong BE, Abriba C, Arikpo GE, Anwan EE, Enyi-Indoh KH. A comparative assessment of the antimicrobial effects of garlic (Allium sativum) and antibiotics on diarrheagenic organisms. Southeast Asian J Trop Med Public Health. 2007;38:343–348
  23. Hodge G, Hodge S, Han P. Allium sativum (garlic) suppresses leukocyte inflammatory cytokine production in vitro: potential therapeutic use in the treatment of inflammatory bowel disease. Cytometry. 2002;48:209–215
  24. Naber KG, Roscher K, Botto H, Schaefer V. Oral levofloxacin 500mg once daily in the treatment of chronic bacterial prostatitis. Int J Antimicrob Agents. 2008;32:145–153
  25. Feldberg RS, Chang SC, Kotik AN, Nadler M, Neuwirth Z, Sundstrom DC, et al. In vitro mechanism of inhibition of bacterial growth by allicin. Antimicrob Agents Chemother. 1988;32:1763–1768

PII: S0924-8579(09)00097-1

doi: 10.1016/j.ijantimicag.2009.02.012

International Journal of Antimicrobial Agents
Volume 34, Issue 3 , Pages 215-219 , September 2009