International Journal of Antimicrobial Agents
Volume 35, Issue 4 , Pages 357-361 , April 2010

The designer proline-rich antibacterial peptide A3-APO is effective against systemic Escherichia coli infections in different mouse models

  • Dora Szabo

      Affiliations

    • Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary
    • These authors contributed equally to this study.
  • ,
  • Eszter Ostorhazi

      Affiliations

    • Microbiology Laboratory, Department of Dermatology, Venereology and Dermato-oncology, Semmelweis University, Budapest, Hungary
    • These authors contributed equally to this study.
  • ,
  • Annegret Binas

      Affiliations

    • AiCuris GmbH & Co. KG, Wuppertal, Germany
  • ,
  • Ferenc Rozgonyi

      Affiliations

    • Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary
    • Microbiology Laboratory, Department of Dermatology, Venereology and Dermato-oncology, Semmelweis University, Budapest, Hungary
  • ,
  • Bela Kocsis

      Affiliations

    • Institute of Medical Microbiology, Semmelweis University, Budapest, Hungary
  • ,
  • Marco Cassone

      Affiliations

    • Sbarro Institute for Cancer Research and Molecular Medicine, Temple University, Philadelphia, PA 19122, USA
  • ,
  • John D. Wade

      Affiliations

    • Howard Florey Institute, University of Melbourne, Victoria 3010, Australia
    • School of Chemistry, University of Melbourne, Victoria 3010, Australia
  • ,
  • Oliver Nolte

      Affiliations

    • AiCuris GmbH & Co. KG, Wuppertal, Germany
  • ,
  • Laszlo Otvos Jr

      Affiliations

    • Department of Biology, Temple University, Philadelphia, PA 19122, USA
    • Corresponding Author InformationCorresponding author. Present address: Temple University, BioLife Sciences Building, 1900 North 12th Street, Philadelphia, PA 19122, USA. Tel.: +1 215 204 4020; fax: +1 215 204 6646.

Received 2 September 2009 ,Accepted 19 October 2009.

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PII: S0924-8579(09)00490-7

doi: 10.1016/j.ijantimicag.2009.10.015

International Journal of Antimicrobial Agents
Volume 35, Issue 4 , Pages 357-361 , April 2010