International Journal of Antimicrobial Agents
Volume 35, Issue 6 , Pages 613-614 , June 2010

Panton–Valentine leukocidin-producing Staphylococcus aureus necrotising pneumonia: measuring toxin levels in microbiological samples to attest of linezolid clinical efficacy

References 

  1. Yanagihara K, Kihara R, Araki N, Morinaga Y, Seki M, Izumikawa K, et al. Efficacy of linezolid against Panton–Valentine leukocidin (PVL)-positive meticillin-resistant Staphylococcus aureus (MRSA) in a mouse model of haematogenous pulmonary infection. Int J Antimicrob Agents. 2009;34:477–481
  2. Gillet Y, Issartel B, Vanhems P, Fournet JC, Lina G, Bes M, et al. Association between Staphylococcus aureus strains carrying gene for Panton–Valentine leukocidin and highly lethal necrotising pneumonia in young immunocompetent patients. Lancet. 2002;359:753–759
  3. Colin DA, Mazurier I, Sire S, Finck-Barbançon V. Interaction of the two components of leukocidin from Staphylococcus aureus with human polymorphonuclear leukocyte membranes: sequential binding and subsequent activation. Infect Immun. 1994;62:3184–3188
  4. Gillet Y, Vanhems P, Lina G, Bes M, Vandenesch F, Floret D, et al. Factors predicting mortality in necrotising community-acquired pneumonia caused by Staphylococcus aureus containing Panton–Valentine leukocidin. Clin Infect Dis. 2007;45:315–321
  5. Dumitrescu O, Boisset S, Badiou C, Bes M, Benito Y, Reverdy ME, et al. Effect of antibiotics on Staphylococcus aureus producing Panton–Valentine leukocidin. Antimicrob Agents Chemother. 2007;51:1515–1519
  6. Gauduchon V, Cozon G, Vandenesch F, Genestier AL, Eyssade N, Peyrol S, et al. Neutralization of Staphylococcus aureus Panton–Valentine leukocidin by intravenous immunoglobulin in vitro. J Infect Dis. 2004;189:346–353
  7. de Bentzmann S, Tristan A, Etienne J, Brousse N, Vandenesch F, Lina G. Staphylococcus aureus isolates associated with necrotising pneumonia bind to basement membrane type I and IV collagens and laminin. J Infect Dis. 2004;190:1506–1515

PII: S0924-8579(10)00071-3

doi: 10.1016/j.ijantimicag.2010.02.002

International Journal of Antimicrobial Agents
Volume 35, Issue 6 , Pages 613-614 , June 2010

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