International Journal of Antimicrobial Agents
Volume 36, Issue 3 , Pages 252-254 , September 2010

Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae and Escherichia coli isolates possessing blaVIM-1 in Greece

Received 25 March 2010 ,Accepted 17 May 2010.

References 

  1. Robicsek A, Jacoby GA, Hooper DC. The worldwide emergence of plasmid-mediated quinolone resistance. Lancet Infect Dis. 2006;6:629–640
  2. Martinez-Martinez L, Pascual A, Jacoby GA. Quinolone resistance from a transferable plasmid. Lancet. 1998;351:797–799
  3. Mendes RE, Bell JM, Turnidge JD, Yang Q, Yu Y, Sun Z, et al. Carbapenem-resistant isolates of Klebsiella pneumoniae in China and detection of a conjugative plasmid (blaKPC-2 plus qnrB4) and a blaIMP-4 gene. Antimicrob Agents Chemother. 2008;52:798–799
  4. Endimiani A, Carias LL, Hujer AM, Bethel CR, Hujer KM, Perez F, et al. Presence of plasmid-mediated quinolone resistance in Klebsiella pneumoniae isolates possessing blaKPC in the United States. Antimicrob Agents Chemother. 2008;52:2680–2682
  5. Chmelnitsky I, Navon-Venezia S, Strahilevitz J, Carmeli Y. Plasmid-mediated qnrB2 and carbapenemase gene blaKPC-2 carried on the same plasmid in carbapenem-resistant ciprofloxacin-susceptible Enterobacter cloacae isolates. Antimicrob Agents Chemother. 2008;52:2962–2965
  6. Wu J-J, Ko W-C, Tsai S-H, Yan JJ. Prevalence of plasmid-mediated quinolone resistance determinants QnrA, QnrB, and QnrS among clinical isolates of Enterobacter cloacae in a Taiwanese hospital. Antimicrob Agents Chemother. 2007;51:1223–1227
  7. Aschbacher R, Doumith M, Livermore DM, Larcher C, Woodford N. Linkage of acquired quinolone resistance (qnrS1) and metallo-β-lactamase (blaVIM-1) genes in multiple species of Enterobacteriaceae from Bolzano, Italy. J Antimicrob Chemother. 2008;61:515–523
  8. Miró E, Segura C, Navarro F, Sorlí L, Coll P, Horcajada JP, et al. Spread of plasmids containing the blaVIM-1 and blaCTX-M genes and the qnr determinant in Enterobacter cloacae, Klebsiella pneumoniae and Klebsiella oxytoca isolates. J Antimicrob Chemother. 2010;65:661–665
  9. Clinical and Laboratory Standards Institute. Performance standards for antimicrobial susceptibility testing. Nineteenth informational supplement. Document M100-S19. Wayne, PA: CLSI; 2009.
  10. Galani I, Rekatsina PD, Hatzaki D, Plachouras D, Souli M, Giamarellou H. Evaluation of different laboratory tests for the detection of metallo-β-lactamase production in Enterobacteriaceae. J Antimicrob Chemother. 2008;61:548–553
  11. Tsakris A, Kristo I, Poulou A, Themeli-Digalaki K, Ikonomidis A, Petropoulou D, et al. Evaluation of boronic acid disk tests for differentiating KPC-possessing Klebsiella pneumoniae in the clinical laboratory. J Clin Microbiol. 2009;47:362–367
  12. Cattoir V, Poirel L, Rotimi V, Soussy CJ, Nordmann P. Multiplex PCR for detection of plasmid-mediated quinolone resistance qnr genes in ESBL-producing enterobacterial isolates. J Antimicrob Chemother. 2007;60:394–397
  13. Vasilaki O, Ntokou E, Ikonomidis A, Sofianou D, Frantzidou F, Alexiou-Daniel S, et al. Emergence of the plasmid-mediated quinolone resistance gene qnrS1 in Escherichia coli isolates in Greece. Antimicrob Agents Chemother. 2008;52:2996–2997
  14. Miriagou V, Tzouvelekis LS, Villa L, Lebessi E, Vatopoulos AC, Carattoli A, et al. CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid. Antimicrob Agents Chemother. 2004;48:3172–3174
  15. Miriagou V, Tzelepi E, Gianneli D, Tzouvelekis LS. Escherichia coli with a self-transferable, multi-resistant plasmid coding for the metallo-β-lactamase VIM-1. Antimicrob Agents Chemother. 2003;47:395–397

PII: S0924-8579(10)00222-0

doi: 10.1016/j.ijantimicag.2010.05.004

International Journal of Antimicrobial Agents
Volume 36, Issue 3 , Pages 252-254 , September 2010

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