« Previous
Next »
International Journal of Antimicrobial Agents
Volume 36, Issue 3
, Pages 222-229
, September 2010
In silico genetic correlations of multidrug efflux pump gene expression in Staphylococcus aureus
References
- . Structure and function of efflux pumps that confer resistance to drugs. Biochem J. 2003;376:313–338
- . Efflux-mediated antimicrobial resistance. J Antimicrob Chemother. 2005;56:20–51
- Use of a genetic approach to evaluate the consequences of inhibition of efflux pumps in Pseudomonas aeruginosa. Antimicrob Agents Chemother. 1999;43:1340–1346
- . Inhibition of the multidrug transporter NorA prevents emergence of norfloxacin resistance in Staphylococcus aureus. Antimicrob Agents Chemother. 1996;40:2673–2674
- . Staphylococcal multidrug efflux protein QacA. J Mol Microbiol Biotechnol. 2001;3:163–170
- . Evidence for the existence of a multidrug efflux transporter distinct from NorA in Staphylococcus aureus. Antimicrob Agents Chemother. 2000;44:1404–1406
- . Characterization of NorR protein, a multifunctional regulator of norA expression in Staphylococcus aureus. J Bacteriol. 2003;185:3127–3138
- . MepR, a repressor of the Staphylococcus aureus MATE family multidrug efflux pump MepA, is a substrate-responsive regulatory protein. Antimicrob Agents Chemother. 2006;50:1276–1281
- . Effect of promoter region mutations and mgrA overexpression on transcription of norA, which encodes a Staphylococcus aureus multidrug efflux transporter. Antimicrob Agents Chemother. 2005;49:161–169
- . σB modulates virulence determinant expression and stress resistance: characterization of a functional rsbU strain derived from Staphylococcus aureus 8325-4. J Bacteriol. 2002;184:5457–5467
- . Reassessment of the number of auxiliary genes essential for expression of high-level methicillin resistance in Staphylococcus aureus. Antimicrob Agents Chemother. 1994;38:2590–2598
- . Alterations of cell wall structure and metabolism accompany reduced susceptibility to vancomycin in an isogenic series of clinical isolates of Staphylococcus aureus. J Bacteriol. 2003;185:7103–7110
- . Methicillin-resistant Staphylococcus aureus clinical strain with reduced vancomycin susceptibility. J Antimicrob Chemother. 1997;40:135–136
- Community-acquired methicillin-resistant Staphylococcus aureus in children with no identified predisposing risk. JAMA. 1998;279:593–598
- . Molecular cloning and nucleotide sequence determination of the regulator region of mecA gene in methicillin-resistant Staphylococcus aureus (MRSA). FEBS Lett. 1992;298:133–136
- . Staphylococcal coagulase; mode of action and antigenicity. J Gen Microbiol. 1952;6:95–107
- . Properties of a cryptic high-frequency transducing phage in Staphylococcus aureus. Virology. 1967;33:155–166
- Complete genomes of two clinical Staphylococcus aureus strains: evidence for the rapid evolution of virulence and drug resistance. Proc Natl Acad Sci USA. 2004;101:9786–9791
- Complete genome sequence of USA300, an epidemic clone of community-acquired meticillin-resistant Staphylococcus aureus. Lancet. 2006;367:731–739
- . Evaluation of a tetracycline-inducible promoter in Staphylococcus aureus in vitro and in vivo and its application in demonstrating the role of sigB in microcolony formation. Infect Immun. 2001;69:7851–7857
- . Molecular genetic analysis of staphylococcal virulence. Methods Microbiol. 1998;27:433–454
- Clinical and Laboratory Standards Institute. Methods for dilution antimicrobial susceptibility tests for bacteria that grow aerobically; approved standard. 7th ed. Document M7-A7. Wayne, PA: CLSI; 2006.
- . Inability of a reserpine-based screen to identify strains overexpressing efflux pump genes in clinical isolates of Staphylococcus aureus. Int J Antimicrob Agents. 2009;33:360–363
- . Multidrug resistance in Staphylococcus aureus due to overexpression of a novel multidrug and toxin extrusion (MATE) transport protein. Antimicrob Agents Chemother. 2005;49:1857–1864
- . Efflux-mediated fluoroquinolone resistance in Staphylococcus aureus. Antimicrob Agents Chemother. 1993;37:1086–1094
- . MgrA is a multiple regulator of two new efflux pumps in Staphylococcus aureus. J Bacteriol. 2005;187:2395–2405
- . NorC, a new efflux pump regulated by MgrA of Staphylococcus aureus. Antimicrob Agents Chemother. 2006;50:1104–1107
- Novel chromosomally encoded multidrug efflux transporter MdeA in Staphylococcus aureus. Antimicrob Agents Chemother. 2004;48:909–917
- . Gene cloning and characterization of SdrM, a chromosomally-encoded multidrug efflux pump, from Staphylococcus aureus. Biol Pharm Bull. 2006;29:554–556
- . Cloning and characterization of a novel chromosomal drug efflux gene in Staphylococcus aureus. Biol Pharm Bull. 2002;25:1533–1536
- . Efflux-related resistance to norfloxacin, dyes, and biocides in bloodstream isolates of Staphylococcus aureus. Antimicrob Agents Chemother. 2007;51:3235–3239
- . Multidrug resistance proteins QacA and QacB from Staphylococcus aureus: membrane topology and identification of residues involved in substrate specificity. Proc Natl Acad Sci USA. 1996;93:3630–3635
- Current protocols in molecular biology. New York, NY: John Wiley and Sons, Inc.; 2005;
- . RNA processing and degradation in Bacillus subtilis. Microbiol Mol Biol Rev. 2003;67:157–174
- . Translation initiation and the fate of bacterial mRNAs. FEMS Microbiol Rev. 2006;30:967–979
- . A mutation in the 5′ untranslated region increases stability of norA mRNA, encoding a multidrug resistance transporter of Staphylococcus aureus. J Bacteriol. 2001;183:2367–2371
- . Mechanisms of fluoroquinolone resistance in genetically related strains of Staphylococcus aureus. Antimicrob Agents Chemother. 1997;41:2733–2737
- . Rapid method for detection of gyrA and grlA mutations in unrelated strains of staphylococci susceptible and resistant to levofloxacin. New Microbiol. 2001;24:347–353
- . Structural and biochemical characterization of MepR, a multidrug binding transcription regulator of the Staphylococcus aureus multidrug efflux pump MepA. Nucleic Acids Res. 2009;37:1211–1224
- . Posttranslational modification influences the effects of MgrA on norA expression in Staphylococcus aureus. J Bacteriol. 2008;190:7375–7381
- . The transcriptional regulators NorG and MgrA modulate resistance to both quinolones and β-lactams in Staphylococcus aureus. J Bacteriol. 2007;189:2996–3005
- . Detection of grlA and gyrA mutations in 344 Staphylococcus aureus strains. Antimicrob Agents Chemother. 1998;42:236–240
- . Bioenergetics of the staphylococcal multidrug export protein QacA. Identification of distinct binding sites for monovalent and divalent cations. J Biol Chem. 1999;274:3541–3548
- . Active export proteins mediating drug resistance in staphylococci. J Mol Microbiol Biotechnol. 2007;12:180–196
- . Messenger RNA turnover processes in Escherichia coli, Bacillus subtilis, and emerging studies in Staphylococcus aureus. Int J Microbiol. 2009;2009:525491
- . Small RNA genes expressed from Staphylococcus aureus genomic and pathogenicity islands with specific expression among pathogenic strains. Proc Natl Acad Sci USA. 2005;102:14249–14254
- . Insertion sequences. Microbiol Mol Biol Rev. 1998;62:725–774
- . Mobile DNA. Washington, DC: ASM Press; 1989;
PII: S0924-8579(10)00234-7
doi: 10.1016/j.ijantimicag.2010.05.015
« Previous
Next »
International Journal of Antimicrobial Agents
Volume 36, Issue 3
, Pages 222-229
, September 2010
